Recombinant Human CHI3L1 (C-6His)

Catalog Number: EKL-PHH0402
Article Name: Recombinant Human CHI3L1 (C-6His)
Biozol Catalog Number: EKL-PHH0402
Supplier Catalog Number: PHH0402
Alternative Catalog Number: EKL-PHH0402-10UG,EKL-PHH0402-50UG,EKL-PHH0402-500UG
Manufacturer: EnkiLife
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Alternative Names: Chitinase-3-Like protein 1, 39 kDa Synovial Protein, Cartilage Glycoprotein 39, CGP-39, GP-39, hCGP-39, YKL-40, CHI3L1
Chitinase-3-Like Protein 1 (CHI3L1) belongs to the glycosyl hydrolase 18 family. CHI3L1 is expressed in activated macrophages, articular chondrocytes, synovial cells as well as in liver. It lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in defense against pathogens, or in tissue remodeling, and in the capacity of cells to respond to and cope with changes in their environment. In addition, CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) which assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.
Molecular Weight: 41.5 KDa
NCBI: 36222
Purity: Greater than 95% as determined by reducing SDS-PAGE
Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.