Recombinant Human DPT (C-Fc-6His)

Product Overview

• Article Name: Recombinant Human DPT (C-Fc-6His)
• Biozol Catalog Number: EKL-PHH0529
• Supplier Catalog Number: PHH0529
• Alternative Catalog Number: EKL-PHH0529-10UG,EKL-PHH0529-50UG,EKL-PHH0529-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP and DPT

Product Description

Dermatopontin, also known as Tyrosine-rich acidic matrix protein, TRAMP and DPT, is a secreted protein which belongs to the dermatopontin family. DPT is expressed in various tissues, such as fibroblasts, heart, skeletal muscle, brain and pancreas. It seems to mediate adhesion by cell surface integrin binding. DPT may serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. DPT can enhance TGFB1 activity through interaction with decorin. In addition, DPT accelerates collagen fibril formation, stabilizes collagen fibrils against low-temperature dissociation and inhibits cell proliferation.

Product Properties

• Molecular Weight: 49.9 KDa
• NCBI: 07507
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.