Recombinant Human IL-10RB (C-6His)

Product Overview

• Article Name: Recombinant Human IL-10RB (C-6His)
• Biozol Catalog Number: EKL-PHH0859
• Supplier Catalog Number: PHH0859
• Alternative Catalog Number: EKL-PHH0859-10UG,EKL-PHH0859-50UG,EKL-PHH0859-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Interleukin-10 receptor subunit beta(IL10RB),Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2

Product Description

IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.

Product Properties

• Molecular Weight: 24.5 KDa
• NCBI: 08334
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.