Interleukin 15 Receptor alpha (IL-15Ralpha) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Ralpha chain can bind soluble IL-15 and ''transpresent cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Ralpha can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Ralpha complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor beta and gamma heterodimers and enables signaling to cells.
Greater than 95% as determined by reducing SDS-PAGE
Application Notes:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
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