Recombinant Human OSMRB (C-6His)

Product Overview

• Article Name: Recombinant Human OSMRB (C-6His)
• Biozol Catalog Number: EKL-PHH0922
• Supplier Catalog Number: PHH0922
• Alternative Catalog Number: EKL-PHH0922-10UG,EKL-PHH0922-50UG,EKL-PHH0922-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Oncostatin-M-Specific Receptor Subunit Beta, Interleukin-31 Receptor Subunit Beta, IL-31 Receptor Subunit Beta, IL-31R Subunit Beta, IL-31R-Beta, IL-31RB, OSMR, OSMRB

Product Description

Oncostatin-M-Specific Receptor Subunit beta (OSMRbeta) is a 150 - 180 kDa member of the IL-6 receptor family. OSMRbeta associates with gp130 to form the type II OSM receptor, the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMRbeta associates with gp130-like receptor (GPL) to form a receptor complex responsive to IL-31. The human OSMRbeta cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmic domain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain, and three Fibronectin type-III domains.

Product Properties

• Molecular Weight: 82.03 KDa
• NCBI: 99650
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.