Recombinant Human Serpin B3 (C-6His)

Catalog Number: EKL-PHH1505
Article Name: Recombinant Human Serpin B3 (C-6His)
Biozol Catalog Number: EKL-PHH1505
Supplier Catalog Number: PHH1505
Alternative Catalog Number: EKL-PHH1505-10UG,EKL-PHH1505-50UG,EKL-PHH1505-500UG
Manufacturer: EnkiLife
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Alternative Names: Serpin B3, Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1,serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3, serpin peptidase inhibitor, clade B (ovalbumin), member 3, Squamous cell carcinoma antigen 1, T4-A,SCCA1
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Molecular Weight: 45.96 KDa
NCBI: 29508
Purity: Greater than 95% as determined by reducing SDS-PAGE
Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.