Recombinant Human Latent TGF Beta-1 (N-6His)

Product Overview

• Article Name: Recombinant Human Latent TGF Beta-1 (N-6His)
• Biozol Catalog Number: EKL-PHH1709
• Supplier Catalog Number: PHH1709
• Alternative Catalog Number: EKL-PHH1709-10UG,EKL-PHH1709-50UG,EKL-PHH1709-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Transforming Growth Factor Beta-1, TGF-Beta-1, Latency-Associated Peptide, LAP, TGFB1, TGFB

Product Description

Transforming Growth Factor beta-1 (TGFbeta-1) is a secreted protein which belongs to the TGF-beta family. TGFbeta-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFbeta-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFbeta-1 peptide. TGFbeta-1 may also form heterodimers with other TGFbeta family members. It has been found that TGFbeta-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

Product Properties

• Molecular Weight: 29.3&12.8 KDa
• NCBI: 01137
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.