Recombinant Human Tie-1 (C-6His)

Product Overview

• Article Name: Recombinant Human Tie-1 (C-6His)
• Biozol Catalog Number: EKL-PHH1754
• Supplier Catalog Number: PHH1754
• Alternative Catalog Number: EKL-PHH1754-10UG,EKL-PHH1754-50UG,EKL-PHH1754-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Tyrosine-Protein Kinase Receptor Tie-1, TIE1, TIE

Product Description

TIE-1 (Tyrosine Kinase with Ig and EGF Homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily. These receptors are expressed on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-1 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18aa signal peptide, a 727 aa extracellular domain and a 354 aa cytoplasmic domain. so far, two ligands have been described for TIE-2 [angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2, but no ligand was found for TIE-1.

Product Properties

• Molecular Weight: 81 KDa
• NCBI: 35590
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.