Recombinant Human CD59 (C-6His)

Product Overview

• Article Name: Recombinant Human CD59 (C-6His)
• Biozol Catalog Number: EKL-PHH2300
• Supplier Catalog Number: PHH2300
• Alternative Catalog Number: EKL-PHH2300-10UG,EKL-PHH2300-50UG,EKL-PHH2300-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: 1F5 antigen, 1F5, 20 kDa homologous restriction factor, CD59 antigen, CD59 glycoprotein, CD59, HRF20, HRF-20, MACIF, MAC-IP, MIC11, MIC11MSK21, MIN1, MIN2, MIN3, MIRL, p18-20, 16.3A5, EL32, FLJ38134, FLJ92039, G344

Product Description

CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL, is an approximately 20 kDa GPI anchored glycoprotein that is an important regulator of the complement system in blood. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Product Properties

• Molecular Weight: 9.8 KDa
• NCBI: 13987
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.