Netrin-G1, known as NTNG-1, and is a member of the UNC-6/Netrin family of proteins. The NTNG1 gene is located on chromosome 1p13.3 and encodes a glycosylphosphatidylinositol protein anchored to the presynaptic membrane. Netrin G1 molecule has been described to be involved in axonal guidance/maintenance and axonal growth cone by specifically interacting with its receptor the Netrin G1 ligand (NGL-1), which is located at the postsynaptic compartment. Netrin Gs knockout mice have disturbed subdendritic laminar organization of their specific synaptic ligands (Ngl1 and Ngl2).
Greater than 95% as determined by reducing SDS-PAGE
Application Notes:
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
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