Recombinant Mouse GHR (C-Fc), Human

Product Overview

• Article Name: Recombinant Mouse GHR (C-Fc), Human
• Biozol Catalog Number: EKL-PHM0763
• Supplier Catalog Number: PHM0763
• Alternative Catalog Number: EKL-PHM0763-10UG,EKL-PHM0763-50UG,EKL-PHM0763-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Alternative Names: growth hormone binding protein, growth hormone receptor, serum binding protein, Somatotropin receptor,GHR, GH receptor, GHBP

Product Description

Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

Product Properties

• Molecular Weight: 58.3 KDa
• NCBI: 3
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.