Recombinant Mouse IL-18BPd (C-Fc), Human

Product Overview

• Article Name: Recombinant Mouse IL-18BPd (C-Fc), Human
• Biozol Catalog Number: EKL-PHM0992
• Supplier Catalog Number: PHM0992
• Alternative Catalog Number: EKL-PHM0992-10UG,EKL-PHM0992-50UG,EKL-PHM0992-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Alternative Names: Interleukin 18 Binding Protein Isoform d, IL-18 BPd,Interleukin-18-binding protein,Interferon gamma-inducing factor-binding protein,Igifbp

Product Description

Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-gamma, which then stimulates 18BP production via NF-kappaB. The interaction between IL-18 and IL-18BP has a significant role in the inflammation process. IL-18 BPs have four isoforms, a, b, c and d, which are spliced by different ways. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain which is essential to the binding and neutralizing properties of the binding proteins. The IL-18 BP isoforms b and d lack a complete Ig domain. The expression of IL-18 and the IL-18BP are indentified in immune tissues such as the spleen, but also in nonimmune cells including keratinocytes.

Product Properties

• Molecular Weight: 45.1 KDa
• NCBI: 9
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.