Recombinant Mouse MARCO (N-8His), Human

Product Overview

• Article Name: Recombinant Mouse MARCO (N-8His), Human
• Biozol Catalog Number: EKL-PHM1134
• Supplier Catalog Number: PHM1134
• Alternative Catalog Number: EKL-PHM1134-10UG,EKL-PHM1134-50UG,EKL-PHM1134-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Alternative Names: Macrophage receptor MARCO, Marco, Macrophage receptor with collagenous structure

Product Description

MARCO (macrophage receptor with collagenous structure) is an 80 kDa type II transmembrane glycoprotein that belongs to the class A scavenger receptor family. Mouse MARCO consists of a 48 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 449 aa extracellular domain (ECD) that includes a stalk region, a collagenlike region, and one SRCR domain. MARCO is constitutively expressed on the surface of splenic and lymph node macrophages. MARCO binds LPS, lipoteichoic acid, and other determinants on Gram positive and Gram negative bacteria. It also binds modified LDL, CpG oligonucleotides, UGRP1, silica, and TiO2.

Product Properties

• Molecular Weight: 46.2 KDa
• NCBI: 60754
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.