Recombinant Cynomolgus TREM-2 (C-6His), Human

Product Overview

• Article Name: Recombinant Cynomolgus TREM-2 (C-6His), Human
• Biozol Catalog Number: EKL-PHV2392
• Supplier Catalog Number: PHV2392
• Alternative Catalog Number: EKL-PHV2392-10UG,EKL-PHV2392-50UG,EKL-PHV2392-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Alternative Names: Ig-like domain-containing protein, TREM2, Triggering receptor expressed on myeloid cells 2

Product Description

TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type-1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes regulated intramembrane proteolysis (RIP). TREM2 is preferentially expressed in microglia and is functionally required for migration, cytokine release, phagocytosis, lipid sensing, ApoE binding, shielding of amyloid plaques, and microglia proliferation in the brian. Most of the functionally investigated mutations are located within the Ig-like domain of TREM2.

Product Properties

• Molecular Weight: 18.3 KDa
• NCBI: 005553122
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.