Tyrphostin AG 1478, CAS [[153436-53-4]]

Product Overview

• Article Name: Tyrphostin AG 1478, CAS [[153436-53-4]]
• Biozol Catalog Number: ENZ-ALX-270-036-M005
• Supplier Catalog Number: ALX-270-036-M005
• Alternative Catalog Number: ENZ-ALX-270-036-M005-5
• Manufacturer: Enzo Life Sciences
• Category: Biochemikalien
• Alternative Names: 4-(3-Chloroanilino)-6,7-dimethoxyquinazoline

Product Description

Potent and selective inhibitor of EGFR (IC50 = 3nM). Reduces EGF-stimulated DNA synthesis in Rat-1 fibroblasts by ~75% at 0.25µM. Blocks EGF-dependent src-family kinase activation and p21/Cip 1/WAF1 induction in A431 cells. Also inhibits H2O2-induced sti

Product Properties

• Molecular Weight: 315.8
• Purity: 98% (HPLC)
• CAS Number: [153436-53-4]
• Formula: C16H14ClN3O2
• Target: EGFR