Non-steroidal anti-inflammatory and analgesic agent. Inhibits cyclooxygenase (IC50=0.1µM) selectively over lipoxygenases (IC50=100µM for 5-, 12- and 15-LO). Preferentially inhibits PGH synthase-1 over PGH synthase-2 (ID50=4.9-8.1 and 130-160µM respective
Molecular Weight:
357.8
Purity:
98% (HPLC)
CAS Number:
[53-86-1]
Formula:
C19H16ClNO4
Target:
COX-1, PPARalpha, PPARgamma
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