Inhibitor of human CDK1 (IC50=4nM), CDK2/cyclin A (IC50=70nM), Cdc2/cyclin B, CDK2/cyclin E (IC50=35nM), CDK4/cyclin D1 (IC50=850nM) as well as CDK5/p35 (IC50=75nM). More membrane permeable than purvalanol B.
Molecular Weight:
388.9
Purity:
99% (NMR)
CAS Number:
[212844-53-6]
Formula:
C19H25N6OCl
Target:
CDK1, CDK2, Cyclin A, Cyclin B, Cyclin E, CDK4, Cyclin D1, CDK5
* VAT and and shipping costs not included. Errors and price changes excepted