Potent inhibitor of CDK1/cyclin B (IC50=35nM). Potent and selective inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50=200nM), CDK5/p25 (IC50=40nM), CDK5/p35 (IC50=40nM) and GSK-3beta . Induces apoptosis by activation of caspase-8 and caspase-9 followed by dis
Molecular Weight:
293.3
Purity:
95%
CAS Number:
[237430-03-4]
Formula:
C16H11N3O3
Target:
CDK1, CDK2, CDK5, GSK-3beta, Caspase-8, Caspase-9
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