Inhibitor of cyclin-dependent kinases (CDKs), with selectivity for CDK1/cyclin B (IC50=55nM), CDK2/cyclin A (IC50=35nM), CDK2/cyclin E (IC50=150nM), CDK4/cyclin D1 (IC50=300nM), CDK5/p35 (IC50=65nM) and GSK-3beta (IC50=280nM).
Molecular Weight:
341.3 . 23.0
Purity:
95% (1H-NMR)
Formula:
C16H9N2O5S . Na
Target:
CDK1, CDK2, CDK4, CDK5, GSK-3beta
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