Cell permeable, potent, selective and ATP-competitive inhibitor of CDK2/cyclin A (IC50=22nM), CDK1/cyclin B (IC50=40nM) and CDK4/cyclin D1 (IC50=200nM). Has no effect on the activity of PKC, p38, PDGFRbeta and EGFR (IC50>10µM). Displays anti-proliferative a
Molecular Weight:
241.3
Purity:
95% (HPLC)
CAS Number:
[377090-84-1]
Formula:
C13H11N3O2
Target:
CDK2, Cyclin A, CDK1, Cyclin B, CDK4
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