Cell permeable, potent, selective, non-transition state and non-competitive inhibitor of gamma-secretase (IC50=0.3nM for total beta-amyloid) and Notch processing, which ceases cell differentiation. At higher concentrations (20-400µM), only weakly affects the pr
Molecular Weight:
490.5
Purity:
95% (HPLC)
CAS Number:
[209986-17-4]
Formula:
C27H24F2N4O3
Target:
gamma-Secretase
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