N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester, gamma-Secretase inhibitor IX
Cell permeable inhibitor of gamma-secretase (IC50=115nM for total beta-amyloid, IC50=200nM for beta-amyloid 1-42). It reduces Abeta levels in vivo in plasma and cerebrospinal fluid in young and aged Tg2576 mice. It blocks the proteolytic processing of neurotrophin re
Molecular Weight:
432.5
Purity:
98% (HPLC)
CAS Number:
[208255-80-5]
Formula:
C23H26F2N2O4
Target:
gamma-Secretase
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