1,000-fold more potent inhibitor of CDK1/cyclin B (IC50=9.5nM) and CDK2/cyclin A3 (IC50=5.4nM) than NU2058 (Prod. No. ALX-270-394). Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50=1.6µM), DYRK1A (IC50=0.9µM), PDK1 (IC50=0.8µM) and ROCKII (IC50=0.6µ
Molecular Weight:
402.5
Purity:
95% (HPLC)
CAS Number:
[444722-95-6]
Formula:
C18H22N6O3S
Target:
CDK1, Cyclin B, CDK2, Cyclin A
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