A cell permeable, highly specific, potent and ATP-competitive inhibitor of Rho kinase (ROCK) (Ki=1.6nM). Exhibits a much weaker affinity for other serine/threonine kinases (Ki=630nM for PKA, 9.27mM for PKC and 10.1mM for MLCK). More potent and selective
Molecular Weight:
319.4 . 73.0
Purity:
98% (TLC)
CAS Number:
[451462-58-1]
Formula:
C16H21N3O2S . 2HCl
Target:
ROCK
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