Selective COX-1 inhibitor (IC50=9nM). Shows 700-fold more selectivity over COX-2 (IC50=6.3µM). Inhibits COX-1-derived platelet thromboxane B2, gastric PGE2, and dermal PGE2 production. Orally active in rat.
Molecular Weight:
352.7
Purity:
98%
CAS Number:
[188817-13-2]
Formula:
C17H12N2OClF3
Target:
COX-1, COX-2
* VAT and and shipping costs not included. Errors and price changes excepted