A cell permeable, selective, and ATP-competitive inhibitor of Rho kinase (ROCK) activity (IC50=25µM). Does not inhibit the activation of Rho nor does it affect the in vitro activities of MLCK, PKCalpha, and SAPK2a/p38alpha. Shown to be less potent than Y-27632 (
Molecular Weight:
194.2
Purity:
98% (HPLC)
CAS Number:
[7272-84-6]
Formula:
C13H10N2
Target:
ROCK
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