Potent inhibitor of PARP-1 and PARP-2 (potency 5nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radiopotentiation. Is toxic to both oxic and hypoxic cells. Enantio
Molecular Weight:
244.3 . 73.0
Purity:
98% (HPLC)
CAS Number:
[912445-05-7]
Formula:
C13H16N4O . 2HCl
Target:
PARP-1, PARP-2
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