ALK5 Inhibitor I, CAS [[396129-53-6]]

Product Overview

• Article Name: ALK5 Inhibitor I, CAS [[396129-53-6]]
• Biozol Catalog Number: ENZ-ALX-270-448-M005
• Supplier Catalog Number: ALX-270-448-M005
• Alternative Catalog Number: ENZ-ALX-270-448-M005-5
• Manufacturer: Enzo Life Sciences
• Category: Biochemikalien
• Alternative Names: TGF-beta RI Kinase Inhibitor I, 3-(Pyridin-2-yl)-4-(4-quinonyl)]-1H-pyrazole

Product Description

Cell permeable, potent, selective and ATP-competitive inhibitor of TGF-beta RI kinase (IC50=51nM). Displays ~15-fold greater selectivity over p38alpha MAPK (IC50=740nM). Inhibits TGF-beta-dependent cellular growth (IC50=89nM in NIH 3T3 mouse fibroblasts) and trans

Product Properties

• Molecular Weight: 272.3
• Purity: 97% (TLC)
• CAS Number: [396129-53-6]
• Formula: C17H12N4
• Target: TGF-beta receptor type 1