Inhibitor of CDK1/cyclin B1 and CDK1/cyclin A. Reversibly arrests human cells at the G2/M border of the cell cycle. Allows for effective cell synchronisation in early mitosis. Downregulates expression of the antiapoptotic proteins Bcl-2 and survivin and
Molecular Weight:
351.4
Purity:
95% (HPLC)
CAS Number:
[872573-93-8]
Formula:
C18H13N3OS2
Target:
CDK1, Cyclin B, Cyclin A
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