Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitocondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-
Molecular Weight:
273.2
Purity:
95% (HPLC, TLC, NMR/ELSD)
CAS Number:
[327033-36-3]
Formula:
C11H6F3NO2S
Target:
pim1
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