Dual inhibitor of 5-lipoxygenase (IC50=8µM) and cyclooxygenase (COX) (IC50=52µM). Also inhibits glutathione S-transferase, induction of nitric oxide (NO) in activated macrophages and inhibits EGF-induced tyrosine phosphorylation of EGF receptors. Antioxi
Molecular Weight:
368.4
Source:
Isolated from turmeric (Curcuma longa).
Purity:
98% (HPLC)
CAS Number:
[458-37-7]
Formula:
C21H20O6
Target:
5-Lipoxygenase, COX, GST, NQO1, NF-kappaB
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