Plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Inhibits normal microtubule asembly and causes aberant tubulin polymerization. Blocks binding of tubulin to microtubule proteins. Induces apoptosis. Triggers
Molecular Weight:
909.1
Source:
Semisynthetic from catharanthine or vindoline.
Purity:
98% (HPLC)
CAS Number:
[143-67-9]
Formula:
C46H58N4O9 . H2SO4
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