A cell permeable, non-pungent TRPV1 antagonist (Ki=5.95µM in rat) that induces apoptosis in U937 cells. Inhibits nitric oxide (NO) production. Also inhibits tumor cell migration in vitro. Is effective against multidrug-resistant cancer cells. Inhibits an
Molecular Weight:
303.4
Source:
Synthetic. Originally isolated from Evodia rutaecarpa.
Purity:
98% (HPLC)
CAS Number:
[518-17-2]
Formula:
C19H17N3O
Target:
TRPV1
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