Cell permeable triterpenoid, anti-inflammatory and immunosuppressive compound. Antioxidant. Suppresses LPS-induced cytokine release in macrophages and monocytes (IC50=40nM for IL-1beta and IL-1alpha, 80nM for IL-6, 110nM for prostaglandin E2 and 210nM for IL-8
Molecular Weight:
450.6
Source:
Isolated from the root of Tripterygium sp.
Purity:
98% (HPLC)
CAS Number:
[34157-83-0]
Formula:
C29H38O4
Target:
Proteasome 20S, Topoisomerase II
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