Aminoglycoside antibiotic that inhibits translation by binding to the small subunit of prokaryotic ribosomes. Inhibitor of phospholipase C (PLC, IC50=1-10µM) due to binding to inositol phospholipids. Neomycin inhibits phosphatidylcholine-phospholipase D
Molecular Weight:
614.7 . 294.2
Purity:
90% (TLC)
CAS Number:
[1405-10-3]
Formula:
C23H46N6O13 . 3H2SO4
Target:
PLC, PLD, Calcium channel
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