Antitumor antibiotic. Catalytic inhibitor of topoisomerase II. Strong protein phosphatase 2A (PP2A) inhibitor (IC50=3.2nM). Weak inhibitor for PP1 (IC50=131µM). No apparent effect on PP2B. The binding site for fostriecin on PP2A is different from that of
Molecular Weight:
452.4
Source:
Synthetic.
Purity:
98% (HPLC)
CAS Number:
[87860-39-7]
Formula:
C19H26O9PNa
Target:
Topoisomerase II, PP2A
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