Antibiotic. Dominant analog of the reveromycin complex. Inhibitor of the mitogenic activity of epidermal growth factor (EGF). G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Displays antiproliferative as well as potent an
Molecular Weight:
660.8
Source:
Isolated from Streptomyces sp. MST-AS5344.
Purity:
99% (HPLC)
Form:
Lyophilized.
CAS Number:
[134615-37-5]
Formula:
C36H52O11
Target:
EGF, Isoleucyl-tRNA synthetase
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