Piericidin A1, Shaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT 143D
Antibiotic. Specific and potent inhibitor of NADH-ubiquinone oxidoreductase (complex I) that binds to ubiquinone binding site(s). Inhibits both mitochondrial and bacterial NADH ubiquinone oxidoreductase. Anticancer agent that prevents up-regulation of GR
Molecular Weight:
415.6
Source:
Isolated from Streptomyces sp. MST-AS5364.
Purity:
95% (HPLC)
CAS Number:
[2738-64-9]
Formula:
C25H37NO4
Target:
NADH-ubiquinone oxidoreductase (complex I)
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