Inhibitor of phosphoinositide-dependent kinase 1 (PDK1). Potent, reversible and ATP-competitive inhibitor of glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) (IC50=5nM). Maintains self-renewal and pluripotency in embryonic stem cells via activation of Wnt in vit
Molecular Weight:
356.2
Purity:
98% (HPLC)
CAS Number:
[667463-62-9]
Formula:
C16H10BrN3O2
Target:
Phosphoinositide-dependent protein kinase 1, GSK-3alpha, GSK-3beta
* VAT and and shipping costs not included. Errors and price changes excepted