Necrox-5(TM) . hydrochloride

Product Overview

• Article Name: Necrox-5(TM) . hydrochloride
• Biozol Catalog Number: ENZ-ALX-430-247-M001
• Supplier Catalog Number: ALX-430-247-M001
• Alternative Catalog Number: ENZ-ALX-430-247-M001-1
• Manufacturer: Enzo Life Sciences
• Category: Sonstiges
• Alternative Names: [5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(tetrahydro-pyran-4-ylmethyl)-amine

Product Description

Cell permeable necrosis inhibitor with antioxidant activity. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1µM NecroX(TM)-5 prevented ~50% cell death in H9C2 cells exposed to 400µM t-BuOOH for 2

Product Properties

• Molecular Weight: 453.6 . 72.9
• Purity: 96% (HPLC, TLC)
• Formula: C25H31N3O3S . 2 HCl

Application Notes

• Application Notes: Can be used for in vitro and in vivo applications.For in vitro experiments, dissolve Necrox-5(TM) in DMSO to 20-50mM stock solution and dilute further in cell culture media. Treat cells with 30µM to 0.1µM final concentration.For in vivo experiments, dissolv