Macrocyclic-triene antibiotic possessing potent immunosuppressant activity. It forms a complex with FKBP12 that binds to an effector, thus inhibiting IL-2 and other growth promoting lymphokines. The effectors were identified as FRAP (FKBP12 rapamycin-ass
Molecular Weight:
914.2
Purity:
98% (HPLC)
CAS Number:
[53123-88-9]
Formula:
C51H79NO13
Target:
Immunophilin, mTOR
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