Necrostatin-1 inhibits necroptosis, a non-apoptotic cell death pathway. Inhibits the loss of mitochondrial membrane potential in TNFalpha-treated Jurkat cells (EC50=490 nM). Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. It
Molecular Weight:
259.3
Purity:
98% (TLC)
CAS Number:
[4311-88-0]
Formula:
C13H13N3OS
Target:
RIP1
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