Induces autophagy in HeLa cells followed by apoptotic cell death (IC50=10µM). This cellular response has been found to be mediated via inhibition of mTORC1 and induction of ER stress (IC50 for BT474 cells=2.5µM and MDAMB231 cells=6µM). The pro-apoptotic
Molecular Weight:
740.9
Purity:
96% (HPLC)
CAS Number:
[41059-79-4]
Formula:
C39H64O13
Target:
mTOR
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