AP-18 is a novel TRPA1 channel blocker (CHO cells, IC50= 3.1µM, human and mouse cell lines, IC50= 4.5µM). It reduces cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced a
Molecular Weight:
209.7
Purity:
98% (TLC)
CAS Number:
[55224-94-7]
Formula:
C11H12CINO
Target:
TRPA1
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