Nucleoside antibiotic. Inhibits protein N-glycosylation by blocking the transfer of N-acetylglucosamine 1-phosphate to dolichol monophosphate. Induces ER-stress following the inhibition of N-linked glycosylation. Arrests cell cycle in late G1. Unstable a
Molecular Weight:
Avg. 840.0
Source:
Isolated from Streptomyces lysosuperficus.
Purity:
99% (TLC)
CAS Number:
[11089-65-9]
Formula:
C38H62N4O16 (Tun B)
Target:
GlcNAc phosphotransferase
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