Shikonin inhibits TNF-alpha- and B6 melanoma-induced angiogenesis in mice. It blocks expression of integrin alphavbeta3 and inhibits endothelial cell proliferation and migration in vitro.
Molecular Weight:
288.3
Source:
Shikonin is a napthoquinone isolated from the roots of Lithospermum erythrorhizon, a component of the traditional Chinese herbal remedy Shiunko.
Purity:
98% (HPLC)
CAS Number:
[517-89-5]
Formula:
C16H16O5
Target:
CD51, CD61
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