Alkaloid isolated from soil fungi. General, cell permeable protein kinase inhibitor. Acts by binding to the ATP binding domain of the kinase. Potent inhibitor of Ca2+/calmodulin kinase II. Inhibits myosin light chain kinase, cAMP-dependent protein kinase
Molecular Weight:
467.5
Purity:
98% (HPLC)
CAS Number:
[99533-80-9]
Formula:
C27H21N3O5
Target:
PKC, MLCK, PKG, CaM kinase II, PKA, Trk
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