Marine sesterterpenoid. Irreversibly inhibits human synovial phospholipase A2 (PLA2, IC50=0.02-0.2µM depending on substrate) as well as bee (IC50=0.05µM) and cobra venom (IC50=2µM) PLA2 by covalently modifying lysine residues. Inhibits human recombinant
Molecular Weight:
416.6
Purity:
98% (TLC)
CAS Number:
[75088-80-1]
Formula:
C25H36O5
Target:
sPLA2, PLC, Calcium channel
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