Tyrphostin AG 370, Tyrphostin B7, 2-Amino-4-(1H-indol-5-yl)-1,1,3-tricyanobuta-1,3-diene
Member of the tyrphostin family of tyrosine kinase inhibitors. Selective inhibitor of the PDGF receptor kinase (IC50=20µM) vs. the EGF receptor kinase (IC50=820µM). Inhibits PDGF-induced mitogenesis in human bone marrow fibroblasts.
Molecular Weight:
287.3
Purity:
99% (TLC)
CAS Number:
[134036-53-6]
Formula:
C15H9N5
Target:
PDGF receptor
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