RG-13022 is a non-phenolic tyrphostin analog, which inhibits the EGF receptor (IC50=5 µM) and PDGF receptor tyrosine kinases, and is long-acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=1 µM) as well as tumor growth in vivo. It inhibits
Molecular Weight:
266.3
Purity:
98% (TLC)
CAS Number:
[136831-48-6]
Formula:
C16H14N2O2
Target:
EGFR, PDGF receptor
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